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Dr Ioana Slabu and Benedict Bauer with the nanomodified stent. Photo Peter Winandy
30.03.2023

Nanomodified polymerstent: Novel technology for tumour therapy

  • Electromagnetically heatable nanomodified stent for the treatment of hollow organ tumours wins second place at the RWTH Innovation Award

Almost every fourth person who dies of cancer has a hollow organ tumour, for example in the bile duct or in the oesophagus. Such a tumour cannot usually be removed surgically. It is only possible to open the hollow organ for a short time using a stent, i.e. a tubeshaped prosthesis. However, the tumour grows back and penetrates the hollow organ through the stent. Ioana Slabu from the Institute of Applied Medical Technology and Benedict Bauer from the Institut für Textiltechnik of RWTH Aachen University have now developed a novel technology for the therapy of hollow organ tumours, which was awarded second place in the RWTH Innovation Award. This involves a polymerstent that contains magnetic nanoparticles. When electromagnetic fields are applied, these nanoparticles lead to a controlled heating of the stent material and thus of the tumour. Because the tumour reacts much more sensitively to heat than healthy tissue, it is destroyed and the hollow organ remains open. Thus, the stent develops a self-cleaning effect.  

  • Electromagnetically heatable nanomodified stent for the treatment of hollow organ tumours wins second place at the RWTH Innovation Award

Almost every fourth person who dies of cancer has a hollow organ tumour, for example in the bile duct or in the oesophagus. Such a tumour cannot usually be removed surgically. It is only possible to open the hollow organ for a short time using a stent, i.e. a tubeshaped prosthesis. However, the tumour grows back and penetrates the hollow organ through the stent. Ioana Slabu from the Institute of Applied Medical Technology and Benedict Bauer from the Institut für Textiltechnik of RWTH Aachen University have now developed a novel technology for the therapy of hollow organ tumours, which was awarded second place in the RWTH Innovation Award. This involves a polymerstent that contains magnetic nanoparticles. When electromagnetic fields are applied, these nanoparticles lead to a controlled heating of the stent material and thus of the tumour. Because the tumour reacts much more sensitively to heat than healthy tissue, it is destroyed and the hollow organ remains open. Thus, the stent develops a self-cleaning effect.  

Ioana Slabu of the AME explains: "Not only can we drastically reduce treatment costs, but above all we can provide relief for millions of patients worldwide.
 
A manufacturing process and proof of concept for magnetic hyperthermia are already in place. This novel technology has a very high development potential because it can also be used for tumours in other parts of the body such as the prostate, stomach, intestine or urinary bladder or for cardiovascular diseases.  

The AiF/IGF project started under the project title "ProNano" funded by BMWK. Now the approval for the follow-up project "ProNano2" has also been received. The approved project is called: "Validation of the innovation potential of heatable stents for heat-induced treatment of cavity tumours" and is funded by BMBF in course of the VIP+ program. With the Clinic for General, Visceral and Transplantation Surgery of the University Hospital Aachen and the Institute for Technology and Innovation Management at RWTH Aachen University, the consortium is enriched by clinical and economic expertise. Every year, RWTH Aachen University honours particularly innovative university projects with the Innovation Award. Professor Malte Brettel, Prorector for Business and Industry, presented the certificates to four outstanding projects as part of RWTHtransparent.

Source:

ITA – Institut für Textiltechnik of RWTH Aachen University

Elke Katz (c) CHT
Elke Katz
05.11.2021

Elke Katz joins the board of the Beitlich Family Foundation

The Beitlich Family Foundation, owner of the CHT Group, has appointed Elke Katz as an additional member of the Foundation's Board of Directors, which includes the function of Supervisory Board, on 1 September 2021. Elke Katz is currently CEO of ratioform Verpackungen GmbH, a company of the Haniel Group, based in Munich.

She has extensive, cross-industry experience in strategic and operational corporate management at companies such as BMW and Telefonica. She holds a degree in business engineering and has extensive know-how in customer experience management, digital business and business development.

Johan de Ruiter, Chairman of the Board of the Beitlich Family Foundation: "We aligned ourselves with the UN's 17 Sustainable Development Goals several years ago and defined sustainability, digitalisation and diversity as important strategic components for the CHT Group. We are therefore delighted to have gained a proven digitisation expert for our board. We are certain that Elke Katz will give us further impetus on this path so that we continue to be a leading, modern and innovative company.”

The Beitlich Family Foundation, owner of the CHT Group, has appointed Elke Katz as an additional member of the Foundation's Board of Directors, which includes the function of Supervisory Board, on 1 September 2021. Elke Katz is currently CEO of ratioform Verpackungen GmbH, a company of the Haniel Group, based in Munich.

She has extensive, cross-industry experience in strategic and operational corporate management at companies such as BMW and Telefonica. She holds a degree in business engineering and has extensive know-how in customer experience management, digital business and business development.

Johan de Ruiter, Chairman of the Board of the Beitlich Family Foundation: "We aligned ourselves with the UN's 17 Sustainable Development Goals several years ago and defined sustainability, digitalisation and diversity as important strategic components for the CHT Group. We are therefore delighted to have gained a proven digitisation expert for our board. We are certain that Elke Katz will give us further impetus on this path so that we continue to be a leading, modern and innovative company.”

The Beitlich Family Foundation consists of 5 members, in addition to Elke Katz and Johan de Ruiter, Prof. Dr.-Ing. Götz Gresser (Vice Chairman), Dr. Antje von Dewitz and Prof. Dr. Klaus Müller.

More information:
CHT Group Beitlich
Source:

CHT Germany GmbH

09.10.2018

JEC Group announces appointment of CEO and JEC World event Director

ERIC PIERREJEAN, CEO OF JEC GROUP

Mr. Eric PIERREJEAN, who joined the company in January, has been appointed Chief Executive Officer, succeeding to Mrs. Frédérique MUTEL. He will be in charge of the further development of the company after two decades of growth under Mrs. MUTEL leadership, dedicated to the development and the promotion of the composite materials industry. Before joining JEC Group, Eric PIERREJEAN was Division General Manager at Comexposium from 2011 to 2017. Prior to this, he spent much of his career in sales and marketing positions, spending more than 15 years in the automotive sector (BMW Group, Land Rover) as well as in the sports goods industry (Nike).

ADELINE LARROQUE, EVENTS DIRECTOR FOR EMEA

ERIC PIERREJEAN, CEO OF JEC GROUP

Mr. Eric PIERREJEAN, who joined the company in January, has been appointed Chief Executive Officer, succeeding to Mrs. Frédérique MUTEL. He will be in charge of the further development of the company after two decades of growth under Mrs. MUTEL leadership, dedicated to the development and the promotion of the composite materials industry. Before joining JEC Group, Eric PIERREJEAN was Division General Manager at Comexposium from 2011 to 2017. Prior to this, he spent much of his career in sales and marketing positions, spending more than 15 years in the automotive sector (BMW Group, Land Rover) as well as in the sports goods industry (Nike).

ADELINE LARROQUE, EVENTS DIRECTOR FOR EMEA

Mrs. Adeline LARROQUE joins JEC Group as Show Director JEC World and EMEA Events with more than 15 years of Global work experience as she has worked in several countries such as USA, UK, China, India, Qatar and UAE where she has developed a strong skill set in exhibitions and events management. After a successful experience at Reed Exhibitions France and China managing numerous exhibitions in the Aerospace, Material, Security, Maritime, Logistics, Construction and Medical industries, she then worked for Qatar Tourism Authority as Head of Exhibitions driving growth for the Doha Jewellery Show, Qatar Motor Show and Women Fashion exhibitions. Lately, she worked for the Events division of the Daily Mail Group supervising the Abu Dhabi International Petroleum Exhibition and Conference as Event Director.

More information:
JEC Group
Source:

APOCOPE